Prolonged consumption of omeprazole may lead to dementia.
Omeprazole is the second most consumed drug in the world, the anti-ulcer class that reduces acid secretion the product is used by those with reflux esophagitis; gastritis; heartburn; duodenal ulcer; stomach ulcer and other treatments, but often people use this drug without going through a doctor who is a great problem because in addition to not be shown self-medication, prolonged use of omeprazole may lead to dementia seconds study published in the Journal of the American Medical Association ( JAMA ).
The news did not surprise the doctors, "For more than five years doctors had been hearing about the existence of all these Secondary effects. The advent of omeprazole according skilled was a revolution in the treatment of gastric ulcers; It is the main indications of the drug.
The study assessed the relationship between the continuous consumption (for two years or more) of high doses of omeprazole, which 40 correspond to milligrams daily and the lack of vitamin B12 in the body, which can lead to neurological disorders severe, and anemia such as dementia. For 14 years (1997-2011), the experts made the comparison between a group of 25 956 patients with vitamin B12 deficiency, with another 184,199 people without this disorder.
The study found that people who took omeprazole or similar for a long time were 65% more likely to have low levels of B12. Patients who are taking it upon medical appointments need not worry. The search, however, recommended that people should self-medicate at least reduce the amount of drug by half, or at least take breaks from one period to another use. Thus, part of the necessary amount of vitamin B12 could be recovered by the body. But outside the study proper is to never use the drug without medical advice.
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